One joined CHIL in January 2015 and leads the Biomarker team. She is responsible for leading CHIL research programs, working with leadership to design studies, analyse complex datasets and disseminate findings. In addition she has oversight of clinical trial data from the lab and advises the Endpoints team as needed. As the Biomarker lead, her team develops new assays and pursues novel research, collaborating with local and international researchers to manage and drive new projects.
Originally from Botswana, One completed her PhD in June 2014 at the University of Cape Town (UCT) in Clinical Sciences and Immunology under supervision and mentorship of Professors Tom Scriba and Willem Hanekom at the South African TB Vaccine Initiative (SATVI). Her work provided novel immunological tools to characterize the memory phenotype and function of TB antigen-specific CD4+ T cells after vaccination and in infection.
One has molecular and flow cytometry assay skills, experience in clinical trials and the application of ISO15189 quality management standards in a research laboratory setting. One retains a Staff Scientist position at Fred Hutch Vaccine and Infectious Disease Division.